1. Physical Activity / Total steps |
NMA |
Direct |
Indirect |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Interpretation of findings |
Number of studies |
Number of patients |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Number of comparisons informing indirect evidence |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
1042.45 [-2268.94, 4353.83] |
Very low |
It may decrease steps but the evidence is very uncertain |
1 |
106 |
1605.0 [-1937.14, 5147.14] |
Low |
1.0 |
-2857.95 [-12184.89, 6468.98] |
Low |
2. Comorbidities managament / Diastolic pressure |
NMA |
Direct |
Indirect |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Interpretation of findings |
Number of studies |
Number of patients |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Number of comparisons informing indirect evidence |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
-0.45 [-4.8, 3.9] |
Very low |
It may have little to no effect on diastolic pressure but the evidence is very uncertain |
1 |
106 |
-1.5 [-6.29, 3.29] |
Low |
1.0 |
4.43 [-5.92, 14.78] |
Low |
3. Comorbidities managament / Systolic pressure |
NMA |
Direct |
Indirect |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Interpretation of findings |
Number of studies |
Number of patients |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Number of comparisons informing indirect evidence |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
-3.17 [-9.82, 3.48] |
Very low |
It may result in little to no difference in systolic pressure |
1 |
106 |
-5.0 [-12.53, 2.53] |
Low |
1.0 |
3.31 [-10.84, 17.46] |
Low |
4. Weight management / Waist size |
NMA |
Direct |
Indirect |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Interpretation of findings |
Number of studies |
Number of patients |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Number of comparisons informing indirect evidence |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
-2.3 [-4.68, 0.09] |
Low |
It may result in little to no difference in waist size |
1 |
106 |
-2.2 [-5.58, 1.18] |
Low |
2.0 |
-2.39 [-5.75, 0.96] |
Low |
5. Weight management / BMI - Body Mass Index |
NMA |
Direct |
Indirect |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Interpretation of findings |
Number of studies |
Number of patients |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Number of comparisons informing indirect evidence |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
-0.8 [-1.9, 0.29] |
Low |
It may result in little to no difference in Body mass index |
1 |
106 |
-0.9 [-2.51, 0.71] |
Low |
2.0 |
-0.72 [-2.22, 0.78] |
Low |
6. Weight management / Weight (Kgs/lbs) |
NMA |
Direct |
Indirect |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Interpretation of findings |
Number of studies |
Number of patients |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Number of comparisons informing indirect evidence |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
-2.18 [-4.71, 0.35] |
Low |
It may result in little to no difference in weight |
2 |
193 |
-2.42 [-5.9, 1.07] |
Low |
2.0 |
-1.91 [-5.59, 1.76] |
Low |
Footnotes per outcome:
1) a) We rated down the certainty of evidence due to very serious risk of bias and very serious imprecision;b) Number of studies included in the network: 31 RCTs; Number of studies directly comparing the intervention with usual care: 1 RCT(s) (N=54); Number of comparison(s) informing the indirect estimate: 1 comparison(s). The range of follow up was from 1 to 24 months for the studies included in the whole network. The range of follow-up was 3 months in the studies directly comparing the self-management intervention versus usual care. 2) a)We rated down the certainty of evidence due to very serious risk of bias, very serious risk of bias, very serious imprecision; b)Number of studies included in the network: 112 RCTs; Number of studies directly comparing the intervention with usual care: 1 RCT(s) (N=54); Number of comparison(s) informing the indirect estimate: 1 comparison(s). The range of follow up was from 1 to 96 months for the studies included in the whole network. The range of follow-up was 3 months in the studies directly comparing the self-management intervention versus usual care. 3) a)We rated down the certainty of evidence due to very serious risk of bias and serious imprecision;b)Number of studies included in the network: 122 RCTs; Number of studies directly comparing the intervention with usual care: 1 RCT(s) (N=54); Number of comparison(s) informing the indirect estimate: 1 comparison(s). The range of follow up was from 1 to 24 months for the studies included in the whole network. The range of follow-up was 3 months in the studies directly comparing the self-management intervention versus usual care. 4) a) We rated down the certainty of evidence due to very serious risk of bias; b) Number of studies included in the network: 178 RCTs; Number of studies directly comparing the intervention with usual care: 1 RCT(s) (N=54); Number of comparison(s) informing the indirect estimate: 2 comparison(s). The range of follow up was from 1 to 24 months for the studies included in the whole network. The range of follow-up was 3 months in the studies directly comparing the self-management intervention versus usual care. 5) a)We rated down the certainty of evidence due to very serious risk of bias; b)Number of studies included in the network: 222 RCTs; Number of studies directly comparing the intervention with usual care: 1 RCT(s) (N=54); Number of comparison(s) informing the indirect estimate: 2 comparison(s). The range of follow up was from 1 to 24 months for the studies included in the whole network. The range of follow-up was 3 months in the studies directly comparing the self-management intervention versus usual care. 6) a) We rated down the certainty of evidence due to very serious of risk of bias; b) Number of studies included in the network: 329 RCTs; Number of studies directly comparing the intervention with usual care: 2 RCT(s) (N=95); Number of comparison(s) informing the indirect estimate: 2 comparison(s). The range of follow up was from 1 to 24 months for the studies included in the whole network. The range of follow-up was 3-12 months in the studies directly comparing the self-management intervention versus usual care.
References of studies informing direct evidence:
1) Young-2015 2) Young-2015 3) Young-2015 4) Young-2015 5) Young-2015 6) Moncrieft-2016b, Young-2015
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