1. Physical activity / Muscle strenght / Exercise capacity |
NMA |
Direct |
Indirect |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Interpretation of findings |
Number of studies |
Number of patients |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Number of comparisons informing indirect evidence |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
1.58 [-0.23, 3.4] |
Very low |
It may increase exercise capacity but the evidence is very uncertain |
0 |
0 |
[, ] |
N/A |
0 |
1.58 [-0.23, 3.4] |
Low |
2. COPD symptoms (short term) / Dyspnea or breathlessness |
NMA |
Direct |
Indirect |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Interpretation of findings |
Number of studies |
Number of patients |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Number of comparisons informing indirect evidence |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
-0.54 [-2.27, 1.18] |
Moderate |
It may decrease dysnea but the evidence is very uncertain |
0 |
0 |
[, ] |
N/A |
1.0 |
-0.54 [-2.27, 1.18] |
0.0 |
3. Coping with the disease, including depression and anxiety / Depression |
NMA |
Direct |
Indirect |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Interpretation of findings |
Number of studies |
Number of patients |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Number of comparisons informing indirect evidence |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
-0.43 [-1.3, 0.45] |
Low |
It may result in little to no difference in depression |
0 |
0 |
[, ] |
N/A |
0.0 |
-0.43 [-1.3, 0.45] |
Low |
4. Qualiy of life / Quality of life (generic instruments) |
NMA |
Direct |
Indirect |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Interpretation of findings |
Number of studies |
Number of patients |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Number of comparisons informing indirect evidence |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
5.55 [3.72, 7.38] |
Low |
It likely results in a large increase quality of life (generic instruments) |
0 |
0 |
[, ] |
N/A |
1.0 |
5.55 [3.72, 7.38] |
Low |
5. Coping with the disease, including depression and anxiety / Anxiety |
NMA |
Direct |
Indirect |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Interpretation of findings |
Number of studies |
Number of patients |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
Number of comparisons informing indirect evidence |
Anticipated absolute effects (95% CI) - Difference |
Certainty of the evidence |
-0.56 [-1.27, 0.16] |
Low |
It may result in a slight decrease in anxiety |
0 |
0 |
[, ] |
N/A |
1.0 |
-0.56 [-1.27, 0.16] |
0.0 |
Footnotes per outcome:
1) We rated down the certainty of evidence due to serious imprecision and serious risk of bias 2) a) We rated down the certainty of evidence due to ,serious risk of bias,very imprecision;b) Number of studies included in the network: 48 RCTs; Number of studies directly comparing the intervention with usual care: 0 RCT(s) (N=0); Number of comparison(s) informing the indirect estimate: 1 comparison(s). 3) a) We rated down the certainty of evidence due to serious risk of bias, and serious imprecision;b) Number of studies included in the network: 30 RCTs; Number of studies directly comparing the intervention with usual care: 0 RCT(s) (N=0); Number of comparison(s) informing the indirect estimate: 0 comparison(s). 4) a) We rated down the certainty of evidence due to very serious of bias; b) Number of studies included in the network: 25 RCTs; Number of studies directly comparing the intervention with usual care: 0 RCT(s) (N=0); Number of comparison(s) informing the indirect estimate: 0 comparison(s). 5) a) We rated down the certainty of evidence due to serious of bias and serious imprecision; b) Number of studies included in the network: 25 RCTs; Number of studies directly comparing the intervention with usual care: 0 RCT(s) (N=0); Number of comparison(s) informing the indirect estimate: 1 comparison(s).
References of studies informing direct evidence:
N/A
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