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The Kilim plot- A tool for visualizing network meta-analysis results for multiple outcomes
The Kilim plot- A tool for visualizing network meta-analysis results for multiple outcomes
Versión 1.0 Aprobado- Tipo del documento
- EXTERNAL_DOCUMENT
- Extensión
- png
- Tamaño
- 182 KB
- Modificado
- 21/10/22 13:46 por mir mir
- Creado
- 21/10/22 13:46 por mir mir
- Localización
- PUBLIC
- Valoraciones
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Versión 1.0Por mir mir, en 21/10/22 13:46Registro sin cambios
Resumen
Network meta-analysis (NMA) can be used to compare multiple competing treatments for the same disease. In practice, usually a range of outcomes is of interest. As the number of outcomes increases, summarizing results from multiple NMAs becomes a nontrivial task, especially for larger networks. Moreover, NMAs provide results in terms of relative effect measures that can be difficult to interpret and apply in every-day clinical practice, such as the odds ratios. In this article, we aim to facilitate the clinical decision-making process by proposing a new graphical tool, the Kilim plot, for presenting results from NMA on multiple outcomes. Our plot compactly summarizes results on all treatments and all outcomes; it provides information regarding the strength of the statistical evidence of treatment effects, while it illustrates absolute, rather than relative, effects of interventions. Moreover, it can be easily modified to include considerations regarding clinically important effects. To showcase our method, we use data from a network of studies in antidepressants. All analyses are performed in R and we provide the source code needed to produce the Kilim plot, as well as an interactive web application.
El proyecto COMPAR-EU ha recibido financiación del programa de investigación e innovación Horizont 2020 de la Unión Europea en virtud del acuerdo de subvención nº 754936.
Tenga en cuenta que ésta es la versión beta de la plataforma COMPAR-EU. Ahora incluye los resultados completos para Diabetes y durante todo el verano de 2022 se completarán los resultados para Obesidad, EPOC e Insuficiencia Cardíaca. La plataforma también se ampliará y mejorará en los próximos meses.